"The results of this study are clinically important as they demonstrate
PEMF has disease modifying activities that may, in the future, provide a
minimally-invasive solution for patients living with painful
degenerative disc disease," said Dr.
In an in-vitro human cell culture and microarray gene expression study, cells were stimulated to elicit the inflammatory environment associated with degenerative disc disease (DDD). The cells were exposed to the Orthofix Physio-Stim® PEMF for four hours daily. At day four, this study revealed that cells treated with PEMF showed a reduction in proinflammatory markers and a decrease in degeneration of the cellular matrix relative to the control group, although this reduction did not persist to day seven.
"We continue to support preclinical evaluation of PEMF technology to
confirm and validate the potential for new clinical applications," said
Intervertebral disc degeneration is one of the most common mechanical
causes of chronic low back pain. It occurs when the usually rubbery
discs lose integrity as a normal process of aging. In 2010, low back
pain was ranked as the third most burdensome condition in terms of
mortality or poor health in the
The Orthofix Physio-Stim and Cervical-Stim®PEMF
technology is approved by the
The paper "Pulsed electromagnetic field (PEMF) treatment reduces
expression of genes associated with disc degeneration in human
intervertebral disc cells" was authored by
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